Attorneys
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Overview
Christina E. Brule, Ph.D., is a registered patent attorney in the firm’s Chemical and Biotech practice groups. Her experience includes trademark prosecution, patent drafting and prosecution, licensing and tech transfer, and general IP counseling.
Before joining HRFM, Christina was a senior research associate at the New York State Science & Technology Law Center. There, she assisted individuals and startups with the IP side of commercializing technology.
Christina has earned the following degrees:
- Bachelor of Science in biochemistry, Nazareth College of Rochester
- Ph.D. in biochemistry, University of Rochester School of Medicine and Dentistry
- Juris Doctor, Syracuse University College of Law
She is a registered patent attorney with the United States Patent and Trademark Office and is admitted to practice law in New York.
Christina is an avid co-op survivalist gamer, skier, hiker and cat mom.
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Publications
- Patents, Trademarks and Copyrights, Oh My! Choosing the Right Form of Intellectual Property Protection, The Daily Record IP Frontiers (July 14, 2026)
- Copyright Claims Board - Overview and Statistics, The Daily Record IP Frontiers (August 11, 2025)
- USPTO Proposed Rulemaking on Terminal Disclaimers, The Daily Record IP Frontiers (July 16, 2024)
- First-Time Filer Expedited Examination Pilot Program, The Daily Record IP Frontiers (March 14, 2023)
- Tips for Choosing and Applying for a Strong Trademark, The Daily Record IP Frontiers (March 14, 2022)
- The TRIPS COVID-19 Waiver, The Daily Record IP Frontiers (May 17, 2021)
- The Copyright Alternative in Small-Claims Enforcement (CASE) Act, The Daily Record IP Frontiers (March 18, 2021)
- Ghoneim, D.H., Zhang, X., Brule, C.E., Mathews, D.H., Grayhack, E.J. (2018). Conservation of Location of Several Specific Inhibitory Codon Pairs in the Saccharomyces sensu stricto Yeasts Reveals Translational Selection. Nucleic Acids Research, 47(3), 1164–1177.
- Brule, C.E. and Grayhack, E.J. (2017). Synonymous Codons: Choose Wisely for Expression. Trends in Genetics, 33(4), 283-297.
- Gamble†, C.E., Brule†, C.E., Dean, K.M., Fields, S., Grayhack, E.J. (2016). Adjacent Codons Act in Concert to Modulate Translation Efficiency in Yeast. Cell, 166(3), 679-690. †co-first authorship
- Brule, C.E., Dean, K.M., Grayhack, E.J. (2016). RNA-ID, a Powerful Tool for Identifying and Characterizing Regulatory Sequences. Methods in Enzymology, 572, 237-253.
- Letzring, D.P., Wolf, A., Brule, C.E., Grayhack, E.J. (2013). Translation of CGA Codon Repeats in Yeast Involves Quality Control Components and Ribosomal Protein L1. RNA, 19(9), 1208-1217.
- News
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Education
- Syracuse University College of Law, J.D., cum laude, 2020; executive editor, Syracuse Law Review
- University of Rochester School of Medicine and Dentistry, Ph.D., biochemistry, 2017
- Nazareth College of Rochester, B.S., biochemistry, magna cum laude, 2011
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Memberships
- New York State Bar Association
- The Hon. David E. Peebles American Inn of Court
- Intellectual Property Owners Association (IPO)
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Admissions
- New York State Bar
- Registered Patent Attorney, United States Patent and Trademark Office